The recognizable homily, "A stitch in time saves nine" truly applies to gastrointestinal (GI) binders. GI binders latch on to noxious chemicals and toxins, rendering them inactive and allowing us to excrete them safely. In the simple act of binding toxins, they are a powerful aid to our own detoxification system, not just in the level of the gut, but also in the liver and kidneys, and in a cellular level within all our cells.
Although we know the importance of gut health, many are unaware of the mechanisms by which intestine health affects detoxification. Toxins, including heavy metals and pesticides or herbicides, are irritating to the mucosal lining of the GI tract and lead to inflammation.1,2,3,4 An inflamed gut lining soon becomes "leaky"--allowing bacterial toxins seep into the bloodstream, where they strongly stimulate our body's inflammatory reaction.5,6 Bacterial endotoxins, and the cascade of inflammatory cytokines they trigger, can also damage the liver and gallbladder, further impairing detoxification.7,8 Exposure to endotoxin also has an impact on detoxification directly, downregulating critical Phase III transporters, the pumps that serve to transport toxins out of our cells and body -- causing us to become even more toxic.9,10 Endotoxin and the related inflammation also leads to glutathione depletion, which contributes to even more damage because we are no longer have the ability to transport toxins out of the cells or shield them from the increased oxidative stress and damage.11,12 What a vicious cycle!
But GI binders can cancel all that. To learn more, people can take a glance at: read. Tried and true organic binders like activated charcoal and clay have been used for centuries as remedies for stomach upset, minor food poisoning, and to promote intestinal cleansing.13 Binders are really a powerful tool in our healing armamentarium, for they can arrest this spiral of inflammation and impaired detoxification until it begins. They are a basic first step to repairing our detoxification channels - encouraging our ability to excrete toxins and so restoring our own detoxification systems.
Not all binders are created equal. There is no universal toxin binder that has an equal affinity for all toxins--bacterial, heavy metal, mold and more. We could line up a pharmacopeia of binders on our kitchen countertop, but which would we choose, and when? A comprehensive blend of GI binders, carefully chosen to provide effective coverage for a range of common toxins and poisonous heavy metals, is an easy and effective approach. Because binders, like charcoal, in their can contribute to constipation, it may be useful to enhance them with additional elements which help bulk up the stool, soothe the intestinal lining, and encourage the balance of healthy gastrointestinal flora for normal motility and function. Here follows a short list of gentle but potent binders that together provide unparalleled synergy and potency.
*Activated Charcoal. The use of activated charcoal to bind toxins dates back to the 1800s. In 1831, a French doctor took a lethal dose of the poison strychnine, standing before the French Academy of Medicine, and suffered no ill effects since he also consumed charcoal at precisely the same time.14 Since that time, the adsorbing ability and clinical advantages of charcoal have been well described.15 Activated charcoal effectively adsorbs pesticides and herbicides,16 mold toxins,17 endotoxin,18 and much more.
Along with its adsorptive properties, charcoal has shown benefits during infections where a person's powerful inflammatory response to a pathogen is potentially damaging. Charcoal has been shown to adsorb and remove the inflammatory molecules related to the immune response (such as interleukins and tumor necrosis factor) that are primary contributors to cellular damage.19 Research indicates it may be useful as an adjunctive therapy for this reason in settings of disease.20
*Bentonite Clay. If you are concerned by history, you will possibly desire to research about hydrogen water. Bentonite clay is also referred to as Montmorillonite clay, for the region in France where it was first found.21 The use of healing clays dates back to ancient civilizations in the Andes, who carried balls of clay for swallowing at will, to protect against poisons and toxins.22 Bentonite clay easily absorbs fluids and their toxins as well, expanding in quantity. Navigate to this webpage results rna acr regen to compare the inner workings of this enterprise. Bentonite clay is very good at absorbing aflatoxin, a mold toxin often found in peanuts and on certain grains,23 pesticides and herbicides,24 and cyanotoxins, found in lakes polluted by harmful algal blooms.25 Bentonite clay also has inherent broad-spectrum antibacterial properties and has a curative effect on the gastrointestinal lining.26
*Chitosan. Derived from shellfish, chitosan is the result of enzymatic treatment of chitin, a component of the shell. Chitin has been used since ancient times, and these instructions can be found in a publication of medicine dating back to the Ming Dynasty: "Split a crab shell, grind it, make a ball out of it and eat it to take care of anything that swells or grows." 27 Chitosan consists of long-chain sugars called oligosaccharides and has a prebiotic effect, promoting the development of friendly Bifidobacterium and Lactobacillus gastrointestinal flora.28 Chitosan can bind to the bile salts that emulsify fat, and thus serves to reduce fat absorption.29 More importantly where detox is concerned, it also binds and removes the conjugated toxins within bile salts. Chitosan binds to many metals as well as polychlorinated biphenyls (PCBs), phthalates, and bisphenol A (BPA), chemicals with many known adverse impacts on health that we are broadly exposed to in the environment.30,31,32,33 Like bentonite clay, chitosan may be a beneficial approach to bacterial infection also, inhibiting the growth of Staphylococcus aureus in one study.34 Chitosan has been shown to have some protective effects against mercury-induced genotoxicity.35
*IMD. The Intestinal Metals Detox (IMD) is a proprietary product that consists of processed silica with covalently attached thiolic metal-binding groups. Get supplementary information on our partner wiki - Visit this link: xeneplex. This proprietary thiol-functionalized silica delivers insoluble thiol groups to bind and eliminate mercury and other heavy metals accumulated in the intestines, and directly quenching free-radicals. Both the silica base as well as the binding agents out-compete other chemicals for metals in the intestines. IMD does not enter the bloodstream, and thus it doesn't lead to redistribution or surges of mobilized metals that can potentially lead to kidney/liver overload.
Using thiolated resins dates back to the 1970s when they were used to deal with methylmercury (MeHg) poisoning in Iraq, and were found to significantly lower the half-life of MeHg from 61 to 20 days, performing better than penicillamine, a medical metal chelating agent.36,37 IMD intercepts MeHg and other metals trapped in enterohepatic circulation, binding them and escorting them from the intestines.38 By doing this, this allows organ and tissue bound mercury to safely drain in the blood at a natural speed.
*Aloe and Acacia Gum. Both aloe and acacia gum are healing and soothing to the gastrointestinal tract, and may offset the constipation which may occasionally occur with the use of GI binders. Acacia gum contains water-soluble dietary fibers that have a prebiotic effect, stimulating the development of favorable Bifidobacterium and Lactobacillus bacteria in the gut, in addition to improving levels of butyrate, a short-chain fatty acid with anti-inflammatory effects which also helps reduce intestinal permeability.39,40 Bifidobacteria support the reduction of the damaging endotoxin, and normalize gut function, reducing irritation and inflammation.41,42 Acacia gum also has antioxidant and free-radical scavenging action.43 As a prebiotic fiber it is well tolerated at high doses using significantly less symptoms than other prebiotics such as fructooligosaccharide (FOS).
Aloe vera is best known for the soothing effect it has, commonly being found around many households and used topically for mild burns to the skin. The topical soothing properties are not only experienced by the skin, and it has a long history of usage for various gastrointestinal conditions related to inflammation: peptic ulcer disease, gastritis, and inflammatory bowel disease.44,45,46 Aloe vera gel has been shown to have immunomodulatory, antioxidant, and anti-inflammatory effects, which may support healing in a number of settings.47,48,49.